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A conserved TLR5 binding and activation hot spot on flagellin

Flagellin is a bacterial protein that polymerizes into the flagellar filament and is essential for bacterial motility. When flagellated bacteria invade the host, flagellin is recognized by Toll-like receptor 5 (TLR5) as a pathogen invasion signal and eventually evokes the innate immune response. Her...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Song, Wan Seok, Jeon, Ye Ji, Namgung, Byeol, Hong, Minsun, Yoon, Sung-il
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247705/
https://ncbi.nlm.nih.gov/pubmed/28106112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40878
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