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Recombinant expression of TLR5 proteins by ligand supplementation and a leucine-rich repeat hybrid technique
Vertebrate TLR5 directly binds bacterial flagellin proteins and activates innate immune responses against pathogenic flagellated bacteria. Structural and biochemical studies on the TLR5/flagellin interaction have been challenging due to the technical difficulty in obtaining active recombinant protei...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823237/ https://ncbi.nlm.nih.gov/pubmed/22989748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.09.021 |
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