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Molecular Determinants of the Sensitivity to G(q/11)-Phospholipase C-dependent Gating, Gd(3+) Potentiation, and Ca(2+) Permeability in the Transient Receptor Potential Canonical Type 5 (TRPC5) Channel
Transient receptor potential canonical type 5 (TRPC5) is a Ca(2+)-permeable cation channel that is highly expressed in the brain and is implicated in motor coordination, innate fear behavior, and seizure genesis. The channel is activated by a signal downstream of the G-protein-coupled receptor (GPCR...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5247662/ https://ncbi.nlm.nih.gov/pubmed/27920205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755470 |
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