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Bromoenol Lactone Inhibits Voltage-Gated Ca(2+) and Transient Receptor Potential Canonical Channels

Circulating hormones stimulate the phospholipase Cβ (PLC)/Ca(2+) influx pathway to regulate numerous cell functions, including vascular tone. It was proposed previously that Ca(2+)-independent phospholipase A(2) (iPLA(2))-dependent store-operated Ca(2+) influx channels mediate hormone-induced contra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chakraborty, Saikat, Berwick, Zachary C., Bartlett, Paula J., Kumar, Sanjay, Thomas, Andrew P., Sturek, Michael, Tune, Johnathan D., Obukhov, Alexander G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199998/
https://ncbi.nlm.nih.gov/pubmed/21795434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.183673
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