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Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots

Meiotic recombination initiates following the formation of DNA double-strand breaks (DSBs) by the Spo11 endonuclease early in prophase I, at discrete regions in the genome coined “hot spots.” In mammals, meiotic DSB site selection is directed in part by sequence-specific binding of PRDM9, a polymorp...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Getun, Irina V., Wu, Zhen, Fallahi, Mohammad, Ouizem, Souad, Liu, Qin, Li, Weimin, Costi, Roberta, Roush, William R., Cleveland, John L., Bois, Philippe R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247613/
https://ncbi.nlm.nih.gov/pubmed/27821479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00942-15
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