Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots

Meiotic recombination initiates following the formation of DNA double-strand breaks (DSBs) by the Spo11 endonuclease early in prophase I, at discrete regions in the genome coined “hot spots.” In mammals, meiotic DSB site selection is directed in part by sequence-specific binding of PRDM9, a polymorp...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Getun, Irina V., Wu, Zhen, Fallahi, Mohammad, Ouizem, Souad, Liu, Qin, Li, Weimin, Costi, Roberta, Roush, William R., Cleveland, John L., Bois, Philippe R. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247613/
https://ncbi.nlm.nih.gov/pubmed/27821479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00942-15
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