Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots

Meiotic recombination initiates following the formation of DNA double-strand breaks (DSBs) by the Spo11 endonuclease early in prophase I, at discrete regions in the genome coined “hot spots.” In mammals, meiotic DSB site selection is directed in part by sequence-specific binding of PRDM9, a polymorp...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Getun, Irina V., Wu, Zhen, Fallahi, Mohammad, Ouizem, Souad, Liu, Qin, Li, Weimin, Costi, Roberta, Roush, William R., Cleveland, John L., Bois, Philippe R. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247613/
https://ncbi.nlm.nih.gov/pubmed/27821479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00942-15
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