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Organization and roles of nucleosomes at mouse meiotic recombination hotspots

Meiotic double strand breaks (DSBs) occur at discrete regions in the genome coined hotspots. Precisely what directs site selection of these DSBs is hotly debated and in particular it is unclear which chromatin features, and regulatory factors are necessary for a genomic region to initiate and resolv...

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Détails bibliographiques
Auteurs principaux: Getun, Irina V., Wu, Zhen K., Bois, Philippe R.J.
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414400/
https://ncbi.nlm.nih.gov/pubmed/22572955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.20325
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