Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling

Cellular responses to the graded Sonic Hedgehog (Shh) morphogenic signal are orchestrated by three Gli genes that give rise to both transcription activators and repressors. An essential downstream regulator of the pathway, encoded by the tumor suppressor gene Suppressor of fused (Sufu), plays critic...

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Udgivet i:Mol Cell Biol
Main Authors: Zhang, Ziyu, Shen, Longyan, Law, Kelvin, Zhang, Zengdi, Liu, Xiaotong, Hua, Hu, Li, Sanen, Huang, Huijie, Yue, Shen, Hui, Chi-chung, Cheng, Steven Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247608/
https://ncbi.nlm.nih.gov/pubmed/27849569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00421-16
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