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Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling

Cellular responses to the graded Sonic Hedgehog (Shh) morphogenic signal are orchestrated by three Gli genes that give rise to both transcription activators and repressors. An essential downstream regulator of the pathway, encoded by the tumor suppressor gene Suppressor of fused (Sufu), plays critic...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Zhang, Ziyu, Shen, Longyan, Law, Kelvin, Zhang, Zengdi, Liu, Xiaotong, Hua, Hu, Li, Sanen, Huang, Huijie, Yue, Shen, Hui, Chi-chung, Cheng, Steven Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247608/
https://ncbi.nlm.nih.gov/pubmed/27849569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00421-16
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