The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

Invariant natural killer T (iNKT) cells are innate-like lymphocytes that protect against infection, autoimmune disease and cancer. However, little is known about epigenetic regulation of iNKT cell development. Here, we show that the H3K27me3 histone demethylase UTX is an essential cell-intrinsic fac...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Immunol
Päätekijät: Beyaz, Semir, Kim, Ji Hyung, Pinello, Luca, Xifaras, Michael E., Hu, Yu, Huang, Jialiang, Kerenyi, Marc A., Das, Partha P., Barnitz, R. Anthony, Herault, Aurelie, Dogum, Rizkullah, Haining, W. Nicholas, Yilmaz, Ömer H., Passegue, Emmanuelle, Yuan, Guo-Cheng, Orkin, Stuart H., Winau, Florian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247321/
https://ncbi.nlm.nih.gov/pubmed/27992400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3644
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia