The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

Invariant natural killer T (iNKT) cells are innate-like lymphocytes that protect against infection, autoimmune disease and cancer. However, little is known about epigenetic regulation of iNKT cell development. Here, we show that the H3K27me3 histone demethylase UTX is an essential cell-intrinsic fac...

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Detaylı Bibliyografya
Yayımlandı:Nat Immunol
Asıl Yazarlar: Beyaz, Semir, Kim, Ji Hyung, Pinello, Luca, Xifaras, Michael E., Hu, Yu, Huang, Jialiang, Kerenyi, Marc A., Das, Partha P., Barnitz, R. Anthony, Herault, Aurelie, Dogum, Rizkullah, Haining, W. Nicholas, Yilmaz, Ömer H., Passegue, Emmanuelle, Yuan, Guo-Cheng, Orkin, Stuart H., Winau, Florian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247321/
https://ncbi.nlm.nih.gov/pubmed/27992400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3644
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