Sensitization of melanoma cells to alkylating agent-induced DNA damage and cell death via orchestrating oxidative stress and IKKβ inhibition

Nitrosourea represents one of the most active classes of chemotherapeutic alkylating agents for metastatic melanoma. Treatment with nitrosoureas caused severe systemic side effects which hamper its clinical use. Here, we provide pharmacological evidence that reactive oxygen species (ROS) induction a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Redox Biol
Päätekijät: Tse, Anfernee Kai-Wing, Chen, Ying-Jie, Fu, Xiu-Qiong, Su, Tao, Li, Ting, Guo, Hui, Zhu, Pei-Li, Kwan, Hiu-Yee, Cheng, Brian Chi-Yan, Cao, Hui-Hui, Lee, Sally Kin-Wah, Fong, Wang-Fun, Yu, Zhi-Ling
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2017
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247288/
https://ncbi.nlm.nih.gov/pubmed/28107677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.01.010
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia