Peripherally administered orexin improves survival of mice with endotoxin shock

Sepsis is a systemic inflammatory response to infection, accounting for the most common cause of death in intensive care units. Here, we report that peripheral administration of the hypothalamic neuropeptide orexin improves the survival of mice with lipopolysaccharide (LPS) induced endotoxin shock,...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Ogawa, Yasuhiro, Irukayama-Tomobe, Yoko, Murakoshi, Nobuyuki, Kiyama, Maiko, Ishikawa, Yui, Hosokawa, Naoto, Tominaga, Hiromu, Uchida, Shuntaro, Kimura, Saki, Kanuka, Mika, Morita, Miho, Hamada, Michito, Takahashi, Satoru, Hayashi, Yu, Yanagisawa, Masashi
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2016
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245965/
https://ncbi.nlm.nih.gov/pubmed/28035899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21055
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