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Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates
Lasso peptides are a class of bioactive ribosomally synthesized and post-translationally modified peptides (RiPPs), with a threaded knot structure that is formed by an isopeptide bond attaching the N-terminus of the peptide to a side chain carboxylate. Some lasso peptide biosynthetic clusters harbor...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5245167/ https://ncbi.nlm.nih.gov/pubmed/27998080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10389 |
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