Engineered secreted T-cell receptor alpha beta heterodimers.

We have produced a soluble form of a mouse alpha beta T-cell antigen receptor (TCR) by shuffling its variable (V) and constant (C) domains to the C region of an immunoglobulin kappa light chain. These chimeric molecules composed of V alpha C alpha C kappa and V beta C beta C kappa chains were effici...

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Autores principales: Grégoire, C, Rebaï, N, Schweisguth, F, Necker, A, Mazza, G, Auphan, N, Millward, A, Schmitt-Verhulst, A M, Malissen, B
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC52449/
https://ncbi.nlm.nih.gov/pubmed/1716770
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