Engineered secreted T-cell receptor alpha beta heterodimers.

We have produced a soluble form of a mouse alpha beta T-cell antigen receptor (TCR) by shuffling its variable (V) and constant (C) domains to the C region of an immunoglobulin kappa light chain. These chimeric molecules composed of V alpha C alpha C kappa and V beta C beta C kappa chains were effici...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Grégoire, C, Rebaï, N, Schweisguth, F, Necker, A, Mazza, G, Auphan, N, Millward, A, Schmitt-Verhulst, A M, Malissen, B
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1991
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52449/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1716770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.18.8077
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