Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2

BACKGROUND: A dengue virus type 2 (DEN-2 Tonga/74) isolated from a 1974 epidemic was characterized by mild illness and belongs to the American genotype of DEN-2 viruses. To prepare a vaccine candidate, a previously described 30 nucleotide deletion (Δ30) in the 3' untranslated region of DEN-4 ha...

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Autors principals: Blaney, Joseph E, Hanson, Christopher T, Hanley, Kathryn A, Murphy, Brian R, Whitehead, Stephen S
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC524489/
https://ncbi.nlm.nih.gov/pubmed/15461822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-4-39
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