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Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration

High-throughput, target-based screening techniques have been utilized extensively for drug discovery in the past several decades. However, the need for more predictive in vitro models of in vivo disease states has generated a shift in strategy towards phenotype-based screens. Phenotype based screens...

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Detalhes bibliográficos
Publicado no:Mol Cell Neurosci
Main Authors: Cooper, Daniel J., Zunino, Giulia, Bixby, John L., Lemmon, Vance P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243932/
https://ncbi.nlm.nih.gov/pubmed/27444126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2016.07.001
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