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Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration

High-throughput, target-based screening techniques have been utilized extensively for drug discovery in the past several decades. However, the need for more predictive in vitro models of in vivo disease states has generated a shift in strategy towards phenotype-based screens. Phenotype based screens...

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Bibliografski detalji
Izdano u:Mol Cell Neurosci
Glavni autori: Cooper, Daniel J., Zunino, Giulia, Bixby, John L., Lemmon, Vance P.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243932/
https://ncbi.nlm.nih.gov/pubmed/27444126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2016.07.001
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