Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers

IκB Kinase (IKK)α is required for activation of an alternative NF-κB signaling pathway based on processing of the NF-κB2/p100 precursor protein, which associates with RelB in the cytoplasm. This pathway, which activates RelB:p52 dimers, is required for induction of several chemokine genes needed for...

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Main Authors: Bonizzi, Giuseppina, Bebien, Magali, Otero, Dennis C, Johnson-Vroom, Kirsten E, Cao, Yixue, Vu, Don, Jegga, Anil G, Aronow, Bruce J, Ghosh, Gourisankar, Rickert, Robert C, Karin, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524385/
https://ncbi.nlm.nih.gov/pubmed/15470505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600391
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