p38/Sp1/Sp4/HDAC4/BDNF Axis Is a Novel Molecular Pathway of the Neurotoxic Effect of the Methylmercury

The molecular pathways involved in methylmercury (MeHg)-induced neurotoxicity are not fully understood. Since pan-Histone deacetylases (HDACs) inhibition has been found to revert the neurodetrimental effect of MeHg, it appeared of interest to investigate whether the pattern of HDACs isoform protein...

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Vydáno v:Front Neurosci
Hlavní autoři: Guida, Natascia, Laudati, Giusy, Mascolo, Luigi, Valsecchi, Valeria, Sirabella, Rossana, Selleri, Carmine, Di Renzo, Gianfranco, Canzoniero, Lorella M. T., Formisano, Luigi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243805/
https://ncbi.nlm.nih.gov/pubmed/28154524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00008
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