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PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus

PI 3-kinase (PI3K) occurs in the nuclei of a broad range of cell types, and various stimuli elicit PI3K nuclear translocation. However, little is known about the biological function of nuclear PI3K. Here we show that nuclear PI3K and its upstream regulator PIKE mediate the antiapoptotic activity of...

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Detalhes bibliográficos
Main Authors: Ahn, Jee-Yin, Rong, Rong, Liu, Xuesong, Ye, Keqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524338/
https://ncbi.nlm.nih.gov/pubmed/15385964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600392
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