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PIKE-mediated PI3-kinase activity is required for AMPA receptor surface expression

AMPAR (α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid receptor) is an ion channel involved in the formation of synaptic plasticity. However, the molecular mechanism that couples plasticity stimuli to the trafficking of postsynaptic AMPAR remains poorly understood. Here, we show that PIKE (pho...

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Detalhes bibliográficos
Main Authors: Chan, Chi Bun, Chen, Yongjun, Liu, Xia, Tang, Xiaoling, Lee, Chi Wai, Mei, Lin, Ye, Keqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199380/
https://ncbi.nlm.nih.gov/pubmed/21847098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.281
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