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PIKE-mediated PI3-kinase activity is required for AMPA receptor surface expression

AMPAR (α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid receptor) is an ion channel involved in the formation of synaptic plasticity. However, the molecular mechanism that couples plasticity stimuli to the trafficking of postsynaptic AMPAR remains poorly understood. Here, we show that PIKE (pho...

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Bibliografski detalji
Glavni autori: Chan, Chi Bun, Chen, Yongjun, Liu, Xia, Tang, Xiaoling, Lee, Chi Wai, Mei, Lin, Ye, Keqiang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199380/
https://ncbi.nlm.nih.gov/pubmed/21847098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.281
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