Age-Dependent Oxidative DNA Damage Does Not Correlate with Reduced Proliferation of Cardiomyocytes in Humans

BACKGROUND: Postnatal human cardiomyocyte proliferation declines rapidly with age, which has been suggested to be correlated with increases in oxidative DNA damage in mice and plays an important role in regulating cardiomyocyte proliferation. However, the relationship between oxidative DNA damage an...

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Udgivet i:PLoS One
Main Authors: Huang, Yanhui, Hong, Haifa, Li, Minghui, Liu, Jinfen, Jiang, Chuan, Zhang, Haibo, Ye, Lincai, Zheng, Jinghao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242470/
https://ncbi.nlm.nih.gov/pubmed/28099512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170351
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