Age-Dependent Oxidative DNA Damage Does Not Correlate with Reduced Proliferation of Cardiomyocytes in Humans

BACKGROUND: Postnatal human cardiomyocyte proliferation declines rapidly with age, which has been suggested to be correlated with increases in oxidative DNA damage in mice and plays an important role in regulating cardiomyocyte proliferation. However, the relationship between oxidative DNA damage an...

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Bibliographic Details
Published in:PLoS One
Main Authors: Huang, Yanhui, Hong, Haifa, Li, Minghui, Liu, Jinfen, Jiang, Chuan, Zhang, Haibo, Ye, Lincai, Zheng, Jinghao
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242470/
https://ncbi.nlm.nih.gov/pubmed/28099512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170351
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