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Accumulation of DNA damage in the aged hematopoietic stem cell compartment

Aging is associated with loss of functional potential of multiple tissue systems, and there has been significant interest in understanding how tissue specific cells contribute to this decline. DNA damage accumulation has been widely associated with aging in differentiated cell types. However, tissue...

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Pubblicato in:Semin Hematol
Autore principale: Beerman, Isabel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242379/
https://ncbi.nlm.nih.gov/pubmed/28088982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2016.11.001
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