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Senescence‐associated DNA methylation is stochastically acquired in subpopulations of mesenchymal stem cells
Replicative senescence has a major impact on function and integrity of cell preparations. This process is reflected by continuous DNA methylation (DNAm) changes at specific CpG dinucleotides in the course of in vitro culture, and such modifications can be used to estimate the state of cellular senes...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5242294/ https://ncbi.nlm.nih.gov/pubmed/27785870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12544 |
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