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Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype

Melanoma is the most lethal skin cancer. Most deaths from melanoma result from metastases. Semaphorins have been shown to inhibit neuronal and endothelial cell migration, but the effects of semaphorins on tumor metastasis have not been documented. We found that semaphorin 3F (SEMA3F) was markedly do...

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Detalhes bibliográficos
Main Authors: Bielenberg, Diane R., Hida, Yasuhiro, Shimizu, Akio, Kaipainen, Arja, Kreuter, Michael, Kim, Caroline Choi, Klagsbrun, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC524226/
https://ncbi.nlm.nih.gov/pubmed/15520858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421378
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