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Structural Insights into Conformational Differences between DNA/TNA and RNA/TNA Chimeric Duplexes

Threose nucleic acid (TNA) is an artificial genetic polymer capable of heredity and evolution that is studied in the context of RNA chemical etiology. Its simplified four-carbon threose backbone replaces the five-carbon ribose in natural nucleic acids. Nonetheless, TNA forms stable antiparallel Wats...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Anosova, Irina, Kowal, Ewa A., Sisco, Nicholas J., Sau, Sujay, Liao, Jen-yu, Bala, Saikat, Rozners, Eriks, Egli, Martin, Chaput, John C., Van Horn, Wade D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242226/
https://ncbi.nlm.nih.gov/pubmed/27347671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600349
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