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Structural basis for TNA synthesis by an engineered TNA polymerase

Darwinian evolution experiments carried out on xeno-nucleic acid (XNA) polymers require engineered polymerases that can faithfully and efficiently copy genetic information back and forth between DNA and XNA. However, current XNA polymerases function with inferior activity relative to their natural c...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Chim, Nicholas, Shi, Changhua, Sau, Sujay P., Nikoomanzar, Ali, Chaput, John C.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5703726/
https://ncbi.nlm.nih.gov/pubmed/29180809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02014-0
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