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Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase

Replicative DNA polymerases are highly efficient enzymes that maintain stringent geometric control over shape and orientation of the template and incoming nucleoside triphosphate. In a surprising twist to this paradigm, a naturally occurring bacterial DNA polymerase I member isolated from Geobacillu...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Jackson, Lynnette N, Chim, Nicholas, Shi, Changhua, Chaput, John C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649750/
https://ncbi.nlm.nih.gov/pubmed/31170294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz513
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