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Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase

Replicative DNA polymerases are highly efficient enzymes that maintain stringent geometric control over shape and orientation of the template and incoming nucleoside triphosphate. In a surprising twist to this paradigm, a naturally occurring bacterial DNA polymerase I member isolated from Geobacillu...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Jackson, Lynnette N, Chim, Nicholas, Shi, Changhua, Chaput, John C
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649750/
https://ncbi.nlm.nih.gov/pubmed/31170294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz513
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