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Healthy glucocorticoid receptor N363S carriers dysregulate gene expression associated with metabolic syndrome

The glucocorticoid receptor single-nucleotide polymorphism (SNP) N363S has been reported to be associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease. Our aim was to determine how the N363S SNP modifies glucocorticoid receptor signaling in a healthy population of individuals...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Endocrinol Metab
Main Authors: Jewell, Christine M., Katen, Kevin S., Barber, Lisa M., Cannon, Crystal, Garantziotis, Stavros, Cidlowski, John A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241554/
https://ncbi.nlm.nih.gov/pubmed/27600822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00105.2016
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