Phage-Derived Protein Induces Increased Platelet Activation and Is Associated with Mortality in Patients with Invasive Pneumococcal Disease

To improve our understanding about the severity of invasive pneumococcal disease (IPD), we investigated the association between the genotype of Streptococcus pneumoniae and disease outcomes for 349 bacteremic patients. A pneumococcal genome-wide association study (GWAS) demonstrated a strong correla...

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Pubblicato in:mBio
Autori principali: Tunjungputri, Rahajeng N., Mobegi, Fredrick M., Cremers, Amelieke J., van der Gaast-de Jongh, Christa E., Ferwerda, Gerben, Meis, Jacques F., Roeleveld, Nel, Bentley, Stephen D., Pastura, Alexander S., van Hijum, Sacha A. F. T., van der Ven, Andre J., de Mast, Quirijn, Zomer, Aldert, de Jonge, Marien I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241397/
https://ncbi.nlm.nih.gov/pubmed/28096486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01984-16
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