Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway

Current antifungal therapies have limited effectiveness in treating invasive fungal infections. Furthermore, the development of new antifungal is currently unable to keep pace with the urgent demand for safe and effective new drugs. Auranofin, an FDA-approved drug for the treatment of rheumatoid art...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Autores principales: Thangamani, Shankar, Maland, Matthew, Mohammad, Haroon, Pascuzzi, Pete E., Avramova, Larisa, Koehler, Carla M., Hazbun, Tony R., Seleem, Mohamed N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241286/
https://ncbi.nlm.nih.gov/pubmed/28149831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00004
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