Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway

Current antifungal therapies have limited effectiveness in treating invasive fungal infections. Furthermore, the development of new antifungal is currently unable to keep pace with the urgent demand for safe and effective new drugs. Auranofin, an FDA-approved drug for the treatment of rheumatoid art...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Thangamani, Shankar, Maland, Matthew, Mohammad, Haroon, Pascuzzi, Pete E., Avramova, Larisa, Koehler, Carla M., Hazbun, Tony R., Seleem, Mohamed N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241286/
https://ncbi.nlm.nih.gov/pubmed/28149831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00004
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