Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway

Current antifungal therapies have limited effectiveness in treating invasive fungal infections. Furthermore, the development of new antifungal is currently unable to keep pace with the urgent demand for safe and effective new drugs. Auranofin, an FDA-approved drug for the treatment of rheumatoid art...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Front Cell Infect Microbiol
Asıl Yazarlar: Thangamani, Shankar, Maland, Matthew, Mohammad, Haroon, Pascuzzi, Pete E., Avramova, Larisa, Koehler, Carla M., Hazbun, Tony R., Seleem, Mohamed N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2017
Konular:
Microbiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241286/
https://ncbi.nlm.nih.gov/pubmed/28149831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00004
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