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Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy
BACKGROUND: Critically ill patients develop atrophic muscle failure, which increases morbidity and mortality. Interleukin-1β (IL-1β) is activated early in sepsis. Whether IL-1β acts directly on muscle cells and whether its inhibition prevents atrophy is unknown. We aimed to investigate if IL-1β acti...
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Publicado no: | Intensive Care Med Exp |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer International Publishing
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5241267/ https://ncbi.nlm.nih.gov/pubmed/28097512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-016-0115-0 |
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