The E3 ubiquitin ligase TRIM62 and inflammation-induced skeletal muscle atrophy

INTRODUCTION: ICU-acquired weakness (ICUAW) complicates the disease course of critically ill patients. Inflammation and acute-phase response occur directly within myocytes and contribute to ICUAW. We observed that tripartite motif–containing 62 (TRIM62), an E3 ubiquitin ligase and modifier of inflam...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Schmidt, Franziska, Kny, Melanie, Zhu, Xiaoxi, Wollersheim, Tobias, Persicke, Kathleen, Langhans, Claudia, Lodka, Doerte, Kleber, Christian, Weber-Carstens, Steffen, Fielitz, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231194/
https://ncbi.nlm.nih.gov/pubmed/25263070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-014-0545-6
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