The Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-Fungal Immunity and Intestinal Inflammation

CARD9 is a central component of anti-fungal innate immune signaling via C-type lectin receptors, and several immune-related disorders are associated with CARD9 mutations. Here we used a rare CARD9 variant that confers protection against inflammatory bowel disease as an entry point to investigate CAR...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Cao, Zhifang, Conway, Kara L., Heath, Robert J., Rush, Jason S., Leshchiner, Elizaveta S., Ramirez-Ortez, Zaida G., Nedelsky, Natalia B., Huang, Hailiang, Ng, Aylwin, Gardet, Agnès, Cheng, Shih-Chin, Shamji, Alykhan F., Rioux, John D., Wijmenga, Cisca, Netea, Mihai G., Means, Terry K., Daly, Mark J., Xavier, Ramnik J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672733/
https://ncbi.nlm.nih.gov/pubmed/26488816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.10.005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados