FOLLICLE-STIMULATING HORMONE RECEPTOR IS EXPRESSED BY MOST OVARIAN CANCER SUBTYPES AND IS A SAFE AND EFFECTIVE IMMUNOTHERAPEUTIC TARGET

PURPOSE: Define the safety and effectiveness of T-cells re-directed against Follicle-Stimulating Hormone Receptor (FSHR)-expressing ovarian cancer cells. EXPERIMENTAL DESIGN: FSHR expression was determined by Western-blot, immunohistochemistry and Q-PCR in 77 human ovarian cancer specimens from 6 di...

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Pubblicato in:Clin Cancer Res
Autori principali: Perales-Puchalt, Alfredo, Svoronos, Nikolaos, Rutkowski, Melanie R, Allegrezza, Michael J, Tesone, Amelia J, Payne, Kyle K, Wickramasinghe, Jayamanna, Nguyen, Jenny M, O'Brien, Shane W, Gumireddy, Kiranmai, Huang, Qihong, Cadungog, Mark G., Connolly, Denise C, Tchou, Julia, Curiel, Tyler J, Conejo-Garcia, Jose R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241180/
https://ncbi.nlm.nih.gov/pubmed/27435394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0492
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