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SATB1 OVEREXPRESSION DRIVES TUMOR-PROMOTING ACTIVITIES IN CANCER-ASSOCIATED DENDRITIC CELLS

Special AT-rich sequence-binding protein-1 (Satb1) governs genome-wide transcriptional programs. Using a conditional knockout mouse, we find that Satb1 is required for normal differentiation of conventional dendritic cells (DCs). Furthermore, Satb1 governs the differentiation of inflammatory DCs by...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Tesone, Amelia J., Rutkowski, Melanie R., Brencicova, Eva, Svoronos, Nikolaos, Perales-Puchalt, Alfredo, Stephen, Tom L., Allegrezza, Michael J., Payne, Kyle K., Nguyen, Jenny M., Wickramasinghe, Jayamanna, Tchou, Julia, Borowsky, Mark E., Rabinovich, Gabriel A., Kossenkov, Andrew V., Conejo-Garcia, Jose R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767618/
https://ncbi.nlm.nih.gov/pubmed/26876172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.01.056
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