SATB1 OVEREXPRESSION DRIVES TUMOR-PROMOTING ACTIVITIES IN CANCER-ASSOCIATED DENDRITIC CELLS

Special AT-rich sequence-binding protein-1 (Satb1) governs genome-wide transcriptional programs. Using a conditional knockout mouse, we find that Satb1 is required for normal differentiation of conventional dendritic cells (DCs). Furthermore, Satb1 governs the differentiation of inflammatory DCs by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Tesone, Amelia J., Rutkowski, Melanie R., Brencicova, Eva, Svoronos, Nikolaos, Perales-Puchalt, Alfredo, Stephen, Tom L., Allegrezza, Michael J., Payne, Kyle K., Nguyen, Jenny M., Wickramasinghe, Jayamanna, Tchou, Julia, Borowsky, Mark E., Rabinovich, Gabriel A., Kossenkov, Andrew V., Conejo-Garcia, Jose R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767618/
https://ncbi.nlm.nih.gov/pubmed/26876172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.01.056
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