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Neonatal Maternal Separation Alters the Capacity of Adult Neural Precursor Cells to Differentiate into Neurons Via Methylation of Retinoic Acid Receptor Gene Promoter

BACKGROUND: Early life stress is thought to contribute to psychiatric disorders, but the precise mechanisms underlying this link are poorly understood. As neonatal stress decreases adult hippocampal neurogenesis, which, in turn, functionally contributes to many behavioral phenotypes relevant to psyc...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Boku, Shuken, Toda, Hiroyuki, Nakagawa, Shin, Kato, Akiko, Inoue, Takeshi, Koyama, Tsukasa, Hiroi, Noboru, Kusumi, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241093/
https://ncbi.nlm.nih.gov/pubmed/25127741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.07.008
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