Neonatal Maternal Separation Alters the Capacity of Adult Neural Precursor Cells to Differentiate into Neurons Via Methylation of Retinoic Acid Receptor Gene Promoter

BACKGROUND: Early life stress is thought to contribute to psychiatric disorders, but the precise mechanisms underlying this link are poorly understood. As neonatal stress decreases adult hippocampal neurogenesis, which, in turn, functionally contributes to many behavioral phenotypes relevant to psyc...

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發表在:Biol Psychiatry
Main Authors: Boku, Shuken, Toda, Hiroyuki, Nakagawa, Shin, Kato, Akiko, Inoue, Takeshi, Koyama, Tsukasa, Hiroi, Noboru, Kusumi, Ichiro
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241093/
https://ncbi.nlm.nih.gov/pubmed/25127741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.07.008
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