Neonatal Maternal Separation Alters the Capacity of Adult Neural Precursor Cells to Differentiate into Neurons Via Methylation of Retinoic Acid Receptor Gene Promoter

BACKGROUND: Early life stress is thought to contribute to psychiatric disorders, but the precise mechanisms underlying this link are poorly understood. As neonatal stress decreases adult hippocampal neurogenesis, which, in turn, functionally contributes to many behavioral phenotypes relevant to psyc...

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Bibliografiske detaljer
Udgivet i:	Biol Psychiatry
Main Authors:	Boku, Shuken, Toda, Hiroyuki, Nakagawa, Shin, Kato, Akiko, Inoue, Takeshi, Koyama, Tsukasa, Hiroi, Noboru, Kusumi, Ichiro
Format:	Artigo
Sprog:	Inglês
Udgivet:	2014
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5241093/ https://ncbi.nlm.nih.gov/pubmed/25127741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.07.008
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Neonatal Maternal Separation Alters the Capacity of Adult Neural Precursor Cells to Differentiate into Neurons Via Methylation of Retinoic Acid Receptor Gene Promoter

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