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Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and Communication

Allosteric interactions in the Hsp70 proteins are linked with their regulatory mechanisms and cellular functions. Despite significant progress in structural and functional characterization of the Hsp70 proteins fundamental questions concerning modularity of the allosteric interaction networks and hi...

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Publicat a:PLoS Comput Biol
Autors principals: Stetz, Gabrielle, Verkhivker, Gennady M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240922/
https://ncbi.nlm.nih.gov/pubmed/28095400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005299
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