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Targeting autophagy to overcome chemoresistance in acute myleogenous leukemia

Therapeutic inhibition of macroautophagy/autophagy is expected to increase chemosensitivity of cancers and alter tumor-stroma interdependence. The hypoxic, metabolically challenged bone marrow microenvironment confers chemoresistance to leukemia cells. The impact of autophagy inhibition in the conte...

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書目詳細資料
發表在:Autophagy
Main Authors: Piya, Sujan, Andreeff, Michael, Borthakur, Gautam
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240828/
https://ncbi.nlm.nih.gov/pubmed/27797294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1245263
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