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Targeting autophagy to overcome chemoresistance in acute myleogenous leukemia

Therapeutic inhibition of macroautophagy/autophagy is expected to increase chemosensitivity of cancers and alter tumor-stroma interdependence. The hypoxic, metabolically challenged bone marrow microenvironment confers chemoresistance to leukemia cells. The impact of autophagy inhibition in the conte...

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Bibliografske podrobnosti
izdano v:Autophagy
Main Authors: Piya, Sujan, Andreeff, Michael, Borthakur, Gautam
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240828/
https://ncbi.nlm.nih.gov/pubmed/27797294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1245263
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