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Targeting autophagy to overcome chemoresistance in acute myleogenous leukemia
Therapeutic inhibition of macroautophagy/autophagy is expected to increase chemosensitivity of cancers and alter tumor-stroma interdependence. The hypoxic, metabolically challenged bone marrow microenvironment confers chemoresistance to leukemia cells. The impact of autophagy inhibition in the conte...
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Publicado no: | Autophagy |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5240828/ https://ncbi.nlm.nih.gov/pubmed/27797294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1245263 |
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