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Two Adjacent Phenylalanines in the NMDA Receptor GluN2A Subunit M3 Domain Interactively Regulate Alcohol Sensitivity and Ion Channel Gating
The N-methyl-D-aspartate (NMDA) receptor is a key target of ethanol action in the central nervous system. Alcohol inhibition of NMDA receptor function involves small clusters of residues in the third and fourth membrane-associated (M) domains. Previous results from this laboratory have shown that tw...
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Publicado no: | Neuropharmacology |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5240780/ https://ncbi.nlm.nih.gov/pubmed/27876530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.11.013 |
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