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Plant toxin β-ODAP activates integrin β1 and focal adhesion: A critical pathway to cause neurolathyrism

Neurolathyrism is a unique neurodegeneration disease caused by β-N-oxalyl-L-α, β- diaminopropionic (β-ODAP) present in grass pea seed (Lathyrus stativus L.) and its pathogenetic mechanism is unclear. This issue has become a critical restriction to take full advantage of drought-tolerant grass pea as...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tan, Rui-Yue, Xing, Geng-Yan, Zhou, Guang-Ming, Li, Feng-Min, Hu, Wen-Tao, Lambein, Fernand, Xiong, Jun-Lan, Zhang, Sheng-Xiang, Kong, Hai-Yan, Zhu, Hao, Li, Zhi-Xiao, Xiong, You-Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240565/
https://ncbi.nlm.nih.gov/pubmed/28094806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40677
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