TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1

Prostate cancer is a major health issue in the Western world. The most common gene rearrangement in prostate cancer is the TMPRSS2-ERG fusion, which results in aberrant expression of the transcription factor ERG. The insulin-like growth factor-1 receptor (IGF1R) plays a key role in cell growth and t...

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Udgivet i:Oncotarget
Main Authors: Sharon, Shilhav Meisel, Pozniak, Yair, Geiger, Tamar, Werner, Haim
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239482/
https://ncbi.nlm.nih.gov/pubmed/27285981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9837
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