Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

TMPRSS2-ERG gene fusions are the predominant molecular subtype of prostate cancer. Here, we explored the role of TMPRSS2-ERG gene fusion product using in vitro and in vivo model systems. Transgenic mice expressing the ERG gene fusion product under androgen-regulation develop mouse prostatic intraepi...

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Détails bibliographiques
Auteurs principaux: Tomlins, Scott A, Laxman, Bharathi, Varambally, Sooryanarayana, Cao, Xuhong, Yu, Jindan, Helgeson, Beth E, Cao, Qi, Prensner, John R, Rubin, Mark A, Shah, Rajal B, Mehra, Rohit, Chinnaiyan, Arul M
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press Inc. 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244693/
https://ncbi.nlm.nih.gov/pubmed/18283340
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